It can occasionally indicate a serious underlying medical condition. There is no cure for Tinnitus, but there are ways of managing it. ... Certain medications can cause or worsen tinnitus, for example, aspirin, particularly in large doses. People with tinnitus may be over-sensitive to loud noise. Tinnitus is very common, affecting an estimated 50 million adults in the U.S. For most people, the condition is merely an annoyance. In severe cases, however, tinnitus can cause people to have difficulty concentrating and sleeping. It may eventually interfere with work and personal relationships, resulting in psychological distress.